What treatment options are available for your patients?

Nutritional Supplements
  • Your patients living with HIV may develop nutritional deficiencies1,2
  • Nutritional supplements may play a role in boosting caloric intake, but must be taken regularly in order to maintain results3
  • People living with HIV may have reduced caloric intake1,2
  • Appetite stimulants may stimulate a patient's appetite, but do not always address nutritional deficiencies as patients may not choose to consume nutrition-rich foods
  • Some stimulants may have a greater effect on fat than on muscle3,4
  • Some testosterone therapies have been shown to increase lean body mass in patients with HIV-associated Wasting, but not all formulations of therapy are equally effective3,5,6
  • It is recommended that patients receiving testosterone therapy undergo annual prostate examinations along with additional monitoring depending on formulation3,6
  • Anabolic steroids may help increase weight3,7
  • Anabolic steroids should be used with caution in people living with HIV; appropriate monitoring should be conducted3,5
  • Clinical studies have shown growth hormone therapy increases both weight and physical endurance3,8
  • Growth hormone should be used with caution in people living with HIV; appropriate monitoring should be conducted2
  • Progressive resistance training exercises can help develop lean body mass1,3
  • Not all patients have access to proper equipment or training

Proper nutrition and exercise are essential to help address HIV-associated Wasting. Encourage your patients to speak with you about creating an effective exercise routine and diet program.

  • Resistance training exercises have been shown to increase LBM and muscular strength, but patients need proper equipment and training1
  • Light to moderate exercise is safe for people living with HIV1
  • Exercises that may benefit your patients include
    • Aerobic: swimming, cycling, walking
    • Strength training
    • Flexibility training
  • Nutritional counseling has been shown to increase caloric intake in patients1
  • Giving patients supplemental high-calorie drinks, working with them to create a plan for balancing their diet, and targeting specific dietary deficiencies may help patients gain weight

Learn more about a specific treatment option for HIV-associated Wasting

Learn More
References:
  1. Dudgeon WD, Phillips KD, Carson JA, Brewer JA, Durstine JL, Hand GA. Counteracting muscle wasting in HIV-infected individuals. HIV Med. 2006;7(5):299-310.
  2. Wasserman P, Segal-Maurer S, Wehbeh W, Rubin DS. Wasting disease, chronic immune activation, and inflammation in the HIV-infected patient. Top Clin Nutr. 2011;26(1):14-28.
  3. Grinspoon S, Mulligan K; for the Department of Health and Human Services Working Group on the Prevention and Treatment of Wasting and Weight Loss. Weight loss and wasting in patients infected with human immunodeficiency virus. Clin Infec Dis. 2003;36(Suppl 2):S69-S78.
  4. Badowski ME, Perez SE. Clinical utility of dronabinol in the treatment of weight loss associated with HIV and AIDS. HIV AIDS (Auckl). 2016;8:37-45.
  5. Ashby J, Goldmeier D, Sadeghi-Nejad H. Hypogonadism in human immunodeficiency virus-positive men. Korean J Urol. 2014;55:9-16.
  6. Bhasin S, Brito JP, Cunningham GR, et al. Testosterone therapy in men with hypogonadism: an endocrine society clinical practice guideline. J Clin Endocrinol Metab. 2018;103(5):1715-1744.
  7. Tang AM, Jacobson DL, Spiegelman D, Knox TA, Wanke C. Increasing risk of 5% or greater unintentional weight loss in a cohort of HIV-infected patients, 1995 to 2003. J Acquir Immune Defic Syndr. 2005;40(1):70-76.
  8. Moyle GJ, Daar ES, Gertner JM, et al. Growth hormone improves lean body mass, physical performance, and quality of life in subjects with HIV-associated weight loss or wasting on highly active antiretroviral therapy. J Acquir Immune Defic Syndr. 2004;35(4):367-375.
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